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Invitrogen
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Immunogen sequence: SSLGDGCSFP TRLVGMDPEQ ASVTNQNEYA RSSGSNQPFP IKPLSESKNR LLDSESQWLE NGAEEGIVKS GTNNHVTVAI E
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 93%.
Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acyltransferase ZDHHC20; DHHC domain-containing cysteine-rich protein 20; DHHC20; Palmitoyltransferase ZDHHC20; Zinc finger DHHC domain-containing protein 20; zinc finger, DHHC-type containing 20
基因别名: 4933421L13Rik; DHHC-20; ZDHHC20
UniProt ID: (Human) Q5W0Z9
Entrez Gene ID: (Human) 253832