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Invitrogen
ZDHHC21 Polyclonal Antibody
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ZDHHC21 Antibody (PA5-25096) in IHC (P)
Immunohistochemistry analysis of ZDHHC21 in formalin fixed and paraffin embedded human testis tissue. Samples were incubated with ZDHHC21 polyclonal antibody (Product # PA5-25096) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-25096
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 59-87 amino acids from the N-terminal region of human ZDHHC21
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine based on sequence homology.
靶标信息
Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DHHC domain-containing cysteine-rich protein 21; DHHC-21; GABA-A receptor-associated membrane protein 3; GRAMP-3; probable palmitoyltransferase ZDHHC21; unnamed protein product; zinc finger DHHC domain-containing protein 21; zinc finger DHHC-type containing 21; zinc finger DHHC-type palmitoyltransferase 21; zinc finger, DHHC domain containing 21
基因别名: 9130404H11Rik; D130004H04Rik; dep; DHHC-21; DHHC21; DNZ1; HSPC097
UniProt ID: (Human) Q8IVQ6, (Mouse) Q9D270
Entrez Gene ID: (Human) 340481, (Mouse) 68268
regulation of vascular smooth muscle contraction
protein targeting to membrane
peptidyl-L-cysteine S-palmitoylation
nitric oxide metabolic process
adrenergic receptor signaling pathway
regulation of establishment of endothelial barrier
regulation of leukocyte adhesion to arterial endothelial cell
hair follicle development
protein palmitoylation
sebaceous gland development
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