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Invitrogen
ZFHX3 Polyclonal Antibody
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产品信息
PA5-49830
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from internal of human ZFHX3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total ZFHX3 protein.
靶标信息
Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer. Miura Y., J. Biol. Chem. 270:26840-26848(1995). Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991). Martin J., Nature 432:988-994(2004).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha-fetoprotein enhancer binding protein; Alpha-fetoprotein enhancer-binding protein; AT motif binding factor 1; AT motif-binding factor 1; AT-binding transcription factor 1; ZFH-3; Zinc finger homeobox protein 3; Zinc finger homeodomain protein 3
基因别名: A230102L03Rik; ATBF1; ATBT; C16orf47; mKIAA4228; WBP9; ZFHX3; ZNF927
UniProt ID: (Human) Q15911
Entrez Gene ID: (Human) 463, (Mouse) 11906
core promoter sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
zinc ion binding
enzyme binding
nucleic acid binding
DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell cycle arrest
brain development
muscle organ development
circadian regulation of gene expression
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
response to transforming growth factor beta
regulation of locomotor rhythm
transcription, DNA-templated
negative regulation of myoblast differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
