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Invitrogen
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Immunogen sequence: IGPDGHPLTV YPCMICGKKF KSRGFLKRHM KNHPEHLAKK KYHCTDCDYT TNKKISLHNH LESHKLTSKA EKAIECDECG KHFSHAGALF THKMVHKEKG ANKMHKCKFC EYETAEQGLL NRHL
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
ZFX is a member of the Kruppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: X-linked zinc finger protein; Zinc finger X-chromosomal protein
基因别名: ZFX; ZNF926
UniProt ID: (Human) P17010
Entrez Gene ID: (Human) 7543