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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: NHLCPTSSDSL ASVCSPSQLK DDGSIGRDPS MSAITSLTVD SVISSQGTDG CPAVKKQENY IPDEDLTGKI SSPRTDLGSP N
Highest antigen sequence identity to the following orthologs - mouse 62%, rat 60%.
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hSARA; Madh-interacting protein; Mothers against decapentaplegic homolog-interacting protein; Novel serine protease; NSP; Receptor activation anchor; Smad anchor for receptor activation; Zinc finger FYVE domain-containing protein 9
基因别名: MADHIP; SARA; SMADIP; ZFYVE9
Entrez Gene ID: (Human) 9372