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Invitrogen
ZGLP1 Polyclonal Antibody
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产品信息
PA5-62064
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LLDRDSKDTQ TRISQKGRRL QPPGTPSAPP QRRPRKQLNP CRGTERVDPG FEGVTLKFQI KPDSSLQIIP TYSLPCSSRS QE
Highest antigen sequence identity to the following orthologs: Mouse - 50%, Rat - 50%.
靶标信息
Glucagon is initially synthesized as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GATA like protein 1; GATA like protein-1; GATA zinc finger domain containing 3; GATA-like protein 1; GATA-type zinc finger protein 1; GLP-1
基因别名: GATAD3; GLP-1; GLP1; ZGLP1
UniProt ID: (Human) P0C6A0
Entrez Gene ID: (Human) 100125288
