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Positive Samples: LO2, HeLa; Cellular Location: Cell membrane, Cell projection, Multi-pass membrane protein, lamellipodium
Immunogen sequence: EENEQTEEGR PSAVE
The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Factor for adipocyte differentiation 123; FAD-123; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; Metal cation symporter ZIP14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; zinc transporter ZIP14; ZIP-14; Zrt- and Cig19; Zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14
基因别名: cig19; FAD-123; Fad123; HMNDYT2; KIAA0062; LZT-Hs4; NET34; SLC39A14; ZIP-14; ZIP14
UniProt ID: (Human) Q15043, (Mouse) Q75N73
Entrez Gene ID: (Human) 23516, (Rat) 306009, (Mouse) 213053