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Invitrogen
ZMYM4 Polyclonal Antibody
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ZMYM4 Antibody (PA5-89455) in WB
Western blot analysis of ZMYM4 in extracts of various cell lines. Samples were incubated with ZMYM4 Polyclonal antibody (Product # PA5-89455) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-89455
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 35-230 of human ZMYM4 (NP_0050862)
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TEMSEDIDHN LTPTLDSMSY GMPNQTGSEN SLLDEDDYFL NSGDLAGIPV VGSDNEDEQD FSSKDNLVSS IHTDDSLEVE RRVTQHESDN ENEIQIQNKL KKDFPKQFDQ VSVFKSIRKD FSLVRENSKE TFSGKEKNRD LTYEREKRLD KPHKDLDSRL KSSFFDKAAN QVEETLHTHL PQTPETNFRD SSYPFA; Positive Samples: 293T, HepG2, U87, HeLa
靶标信息
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-gamma-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell death inhibiting RNA; MYM type 4; Zinc finger MYM-type protein 4; Zinc finger protein 262; zinc finger, MYM-type 4
基因别名: CDIR; KIAA0425; MYM; ZMYM4; ZNF198L3; ZNF262
UniProt ID: (Human) Q5VZL5
Entrez Gene ID: (Human) 9202
