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Invitrogen
ZNF140 Polyclonal Antibody
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产品信息
PA5-61714
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GKREVKRDLF SVSESSGEIK DFSPKNVIYD DSSQYLIMER ILSQGPVYSS FKGGWKCKDH TEMLQENQGC IRKVTVSHQE AL
Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 26%.
靶标信息
The ZNF140 gene encodes a zinc finger protein that contains KRAB (Kruppel-associated box) domains, which are known to function as transcriptional repressors. These domains are located at the N-terminus of the protein and are involved in mediating protein-protein interactions, critical for gene silencing. ZNF140 is part of a large family of zinc finger proteins, which play significant roles in regulating gene expression by binding to specific DNA sequences. The KRAB domains of ZNF140 enable it to interact with other transcriptional repressors and recruit corepressor complexes, leading to chromatin remodeling and transcriptional repression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zinc finger protein 140
基因别名: pHZ-39; ZNF140
UniProt ID: (Human) P52738
Entrez Gene ID: (Human) 7699
