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Abnova
ZNF259 Polyclonal Antibody, MaxPab™
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产品信息
H00008882-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ZNF259 (NP_003895.1, 1 a.a. approximately 459 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAASGAVEPG PPGAAVAPSP APAPPPAPDH LFRPISAEDE EQQPTEIESL CMNCYCNGMT RLLLTKIPFF REIIVSSFSC EHCGWNNTEI QSAGRIQDQG VRYTLSVRAL EDMNREVVKT DSAATRIPEL DFEIPAFSQK GALTTVEGLI TRAISGLEQD QPARRANKDA TAERIDEFIV KLKELKQVAS PFTLIIDDPS GNSFVENPHA PQKDDALVIT HYNRTRQQEE MLGLQEEAPA EKPEEEDLRN EVLQFSTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS GGAVEPLGTR ITLHITDASD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD IRELVTKNPF TLGDSSNPGQ TERLQEFSQK MDQIIEGNMK AHFIMDDPAG NSYLQNVYAP EDDPEMKVER YKRTFDQNEE LGLNDMKTEG YEAGLAPQR
靶标信息
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zinc finger protein 259; Zinc finger protein ZPR1
基因别名: ZNF259; ZPR1
UniProt ID: (Human) O75312
Entrez Gene ID: (Human) 8882
microtubule cytoskeleton organization
inner cell mass cell proliferation
trophectodermal cell proliferation
mRNA processing
signal transduction
cell proliferation
RNA splicing
positive regulation of gene expression
spinal cord development
Cajal body organization
regulation of myelination
positive regulation of RNA splicing
DNA endoreduplication
positive regulation of protein import into nucleus
positive regulation of growth
axon development
cellular response to epidermal growth factor stimulus
positive regulation of transcription involved in G1/S transition of mitotic cell cycle
apoptotic process involved in development
pre-mRNA catabolic process
negative regulation of motor neuron apoptotic process
