Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ZNF366 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-110893
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human ZNF366. Recombinant protein control fragment (Product #RP-93623).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DLAVKKTPSF PHCLQPVASR GKAPQRHPFP EALRGPFSQF RYEPPPGDLD GFPGVFEGAG SRKRKSMPTK MPYNH
Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 87%.
Target Information
Zinc finger protein 366 (ZNF366), also known as Zinc finger estrogen receptor binding domain-containing protein 1, is a gene located on chromosome 5q31.2 that encodes a transcription factor characterized by zinc finger domains. These domains are crucial for DNA binding, allowing ZNF366 to regulate gene expression by interacting with specific DNA sequences. ZNF366 is involved in modulating the activity of various signaling pathways, including those related to hormone receptors, such as the estrogen receptor, impacting cellular processes like development, differentiation, and proliferation. The protein's specific functional roles are still under investigation, but it is thought to contribute to transcriptional regulation and chromatin remodeling. Altered expression or mutations of ZNF366 have been associated with certain cancers, particularly breast cancer, where its regulatory functions may influence tumorigenesis. Research on ZNF366 continues to explore its potential role in disease mechanisms and therapeutic strategies, particularly in oncology and endocrine-related disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DC-SCRIPT; Dendritic cell-specific transcript protein; Zinc finger protein 366
Gene Aliases: DCSCRIPT; ZNF366
UniProt ID: (Human) Q8N895
Entrez Gene ID: (Human) 167465
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support