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Immunogen sequence: SEMQEYFLRP GTDPQSEKLH GKMSLEHEGL ATADGICSMM IQNQVSPEDA LYGFDSYGPV TDSLIHEGEN SYKFEEMFNE NCFLVQHEQI LPRVKPYDCP ECGKAFGKSK H
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppeltype DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF460 (zinc finger protein 460), also known as HZF8 or ZNF272, is a 562 amino acid nuclear protein that is ubiquitously expressed at low levels and expressed at high levels in pancreas and liver. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZNF460 contains 11 C2 H2-type zinc fingers and a KRAB domain. Like other zinc-fingers, ZNF460 is also suggested to be involved in transcriptional regulation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zinc finger protein 272; Zinc finger protein 460; Zinc finger protein HZF8
基因别名: HZF8; ZNF272; ZNF460
UniProt ID: (Human) Q14592
Entrez Gene ID: (Human) 10794