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Invitrogen
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Immunogen sequence: GKMSLEHEGL ATADGICSMM IQNQVSPEDA LYGFDSYGPV TDSLIHEGEN SYKFEEMFNE NCFLVQHEQI LPRVKPYDC
Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 29%.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppeltype DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF460 (zinc finger protein 460), also known as HZF8 or ZNF272, is a 562 amino acid nuclear protein that is ubiquitously expressed at low levels and expressed at high levels in pancreas and liver. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZNF460 contains 11 C2 H2-type zinc fingers and a KRAB domain. Like other zinc-fingers, ZNF460 is also suggested to be involved in transcriptional regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zinc finger protein 272; Zinc finger protein 460; Zinc finger protein HZF8
基因别名: HZF8; ZNF272; ZNF460
UniProt ID: (Human) Q14592
Entrez Gene ID: (Human) 10794