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The antibody detects endogenous levels of total ZNF50 / ZSCAN22 protein.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GLI-Kruppel family member HKR2; Krueppel-related zinc finger protein 2; Protein HKR2; Zinc finger and SCAN domain-containing protein 22; Zinc finger protein 50
基因别名: HKR2; ZNF50; ZSCAN22
UniProt ID: (Human) P10073
Entrez Gene ID: (Human) 342945