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Invitrogen
ZNF609 Polyclonal Antibody
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ZNF609 Antibody (PA5-144052) in ICC/IF
Immunocytochemistry analysis of ZNF609 in U2OS cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in ZNF609 Polyclonal antibody (Product # PA5-144052) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Rabbit IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate... View More
产品信息
PA5-144052
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human ZNF609 recombinant protein (Position: K865-R1283).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human HEL whole cell, human A549 whole cell. ICC/IF: U20S cell. Flow: HepG2 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The ZNF609 gene encodes zinc finger protein 609, which functions as a transcriptional regulator involved in the modulation of gene expression during development and cellular differentiation. ZNF609 contains zinc finger domains, which enable it to bind DNA and control the transcription of target genes, influencing processes such as cell proliferation and neuronal development. This gene is particularly important for normal neural and muscle cell function and has been implicated in neurodevelopmental disorders and cancer. ZNF609 is known to interact with signaling pathways that control neuron differentiation and migration, and alterations in its expression have been associated with conditions like intellectual disability and developmental delay. Furthermore, ZNF609's role in cancer biology shows its involvement in regulating genes linked to tumor progression and metastasis. Studies on ZNF609 focus on understanding its regulatory mechanisms and potential as a therapeutic target for diseases related to developmental deficits and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zinc finger protein 609
基因别名: KIAA0295; ZNF609
UniProt ID: (Human) O15014
Entrez Gene ID: (Human) 23060
