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Invitrogen
ZNF746 Polyclonal Antibody
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产品信息
PA5-54172
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: WNFRCKPPVG LNPRTGPEGL PYSSPDNGEA ILDPSQAPRP FNEPCKYPGR TKGFGHKPGL KKHP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
靶标信息
ZNF746 is a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and represses transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PARIS; parkin interacting substrate; Parkin-interacting substrate; parkin-interacting sustrate; Zinc finger protein 746
基因别名: PARIS; ZNF746
UniProt ID: (Human) Q6NUN9
Entrez Gene ID: (Human) 155061
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
ubiquitin protein ligase binding
transcription regulatory region DNA binding
metal ion binding
C2H2 zinc finger transcription factor
