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Invitrogen
ZNRF4 Monoclonal Antibody (1A8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-23082
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1A8
抗原
ZNRF4 (NP_859061.2, 108 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.0 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide Sequence: SSSVDFADLP ALFGVPLAPE GIRGYLMEVK PANACHPIEA PRLGNRSLGS IALIRRYDCT FDL
靶标信息
E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2. Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum. Could have a role in spermatogenesis (By similarity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KOX18; nixin; RING finger protein 204; RING-type E3 ubiquitin transferase ZNRF4; unnamed protein product; zinc/RING finger protein 4; ZNF139; ZNF36
基因别名: RNF204; SPERIZIN; spzn; Ssrzf1
UniProt ID: (Human) Q8WWF5
Entrez Gene ID: (Human) 148066
ubiquitin-dependent protein catabolic process
protein ubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of cell cycle
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
negative regulation of intracellular signal transduction
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