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Invitrogen
ZPR1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-83171
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
40 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RYTLSVRALE DMNREVVKTD SAATRIPELD FEIPAFSQKG ALTTVEGLIT RAISGLEQDQ PARRANKDAT AERIDEFIVK LKELKQV
Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 83%.
靶标信息
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: unnamed protein product; zinc finger protein 259
基因别名: GKAF; ZNF259
UniProt ID: (Human) O75312
Entrez Gene ID: (Human) 8882
microtubule cytoskeleton organization
inner cell mass cell proliferation
trophectodermal cell proliferation
DNA replication
protein folding
signal transduction
positive regulation of gene expression
spinal cord development
Cajal body organization
regulation of myelination
positive regulation of RNA splicing
DNA endoreduplication
positive regulation of protein import into nucleus
positive regulation of cell cycle
positive regulation of growth
axon development
cellular response to epidermal growth factor stimulus
apoptotic process involved in development
pre-mRNA catabolic process
negative regulation of motor neuron apoptotic process
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