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Invitrogen
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This antibody is predicted to react with non-human primate based on sequence homology.
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DUB; Lys-63-specific deubiquitinase ZUFSP; zinc finger with UFM1-specific peptidase domain; Zinc finger with UFM1-specific peptidase domain protein; Zinc finger-containing ubiquitin peptidase 1
基因别名: 2700019D07Rik; C6orf113; dJ412I7.3; ZUFSP; ZUP1
UniProt ID: (Human) Q96AP4, (Mouse) Q5FWB1
Entrez Gene ID: (Human) 221302, (Mouse) 72580, (Chinese hamster) 100771141