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Invitrogen
ZUFSP Polyclonal Antibody
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产品信息
PA5-60709
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RINTVQYGTS DNKKDNTLQC GMEVNSSILS GCASNHPKNS AQNLTKDSTL KHEGFYSENL TESRKFLKSR EKQSSLTEIK GSVYETTYSP PECPFCGKIE EHSEDMETHV KTKHANLLDI PLEDCDQPLY DCPMC
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 64%.
靶标信息
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DUB; Lys-63-specific deubiquitinase ZUFSP; Zinc finger with UFM1-specific peptidase domain protein; Zinc finger-containing ubiquitin peptidase 1
基因别名: C6orf113; dJ412I7.3; ZUFSP; ZUP1
UniProt ID: (Human) Q96AP4
Entrez Gene ID: (Human) 221302
