Invitrogen

alpha-1 Antitrypsin Monoclonal Antibody (H8)

Name: alpha-1 Antitrypsin Monoclonal Antibody (H8)
Brand: Invitrogen
SKU: MA5-51077

查看其他69个alpha-1 Antitrypsin抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (8)

alpha-1 Antitrypsin Antibody in Immunocytochemistry (ICC/IF)

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alpha-1 Antitrypsin Antibody (MA5-51077) in ICC/IF

Immunocytochemistry analysis of alpha-1 Antitrypsin in HepG2 cells using alpha-1 Antitrypsin Monoclonal Antibody (H8) (Product # MA5-51077) at a dilution of 30 µg/mL, followed by secondary antibody staining with 2 µg/mL AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.

alpha-1 Antitrypsin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

alpha-1 Antitrypsin Antibody in Western Blot (WB)

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Immunogen image

Immunogen Image alpha-1 Antitrypsin Monoclonal Antibody (H8)

产品信息

MA5-51077

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01-2 µg/mL

免疫组化（石蜡） (IHC (P))

5-20 µg/mL

免疫细胞化学 (ICC/IF)

5-20 µg/mL

产品规格

种属反应

Human, Mouse, Pig, Rat

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

抗原

Recombinant Human a1AT protein, Glu25-Lys418 (Accession #P01009)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% Proclin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_3094361

靶标信息

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: a-1 AT; a1-antitrypsin; AAT; alpha 1 antitrypsin; alpha-1 antitrypsin; Alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; Alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); Alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha-1-protease inhibitor; Alpha-1-proteinase inhibitor; Digestive Zymogen; MGC23330; MGC9222; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; Protease Serine 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; Serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; Serpin A1; Serpin A1a; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; TRP1; TRY1

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基因别名: A1A; A1AT; AAT; Aat-2; Aat2; alpha1AT; Dom1; PI; PI1; PRO0684; PRO2209; PRO2275; SERPINA1; Serpina1a; Spi1; Spi1-1; Spi1-3