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Invitrogen
alpha-1 Microglobulin Polyclonal Antibody
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alpha-1 Microglobulin Antibody (PA5-95955) in WB
Western blot analysis of alpha-1 Microglobulin in extracts of mouse pancreas. Samples were incubated with alpha-1 Microglobulin Polyclonal antibody (Product # PA5-95955) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-95955
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-202 of human AMBP (NP_0016241)
偶联物
形式
Liquid
浓度
1.09 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GPVPTPPDNI QVQENFNISR IYGKWYNLAI GSTCPWLKKI MDRMTVSTLV LGEGATEAEI SMTSTRWRKG VCEETSGAYE KTDTDGKFLY HKSKWNITME SYVVHTNYDE YAIFLTKKFS RHHGPTITAK LYGRAPQLRE TLLQDFRVVA QGVGIPEDSI FTMADRGECV PGEQEPEPIL IPR
Positive Samples: CEM, U-251MG
靶标信息
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AMBP protein; bikunin; complex-forming glycoprotein heterogeneous in charge; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; polyprotein; Protein AMBP; Protein HC; Protein Protein HC; trypstatin; ulinastatin; Urinary Trypsin Inhibitor; uristatin; uronic-acid-rich protein
基因别名: A1M; AI194774; AMBP; ASPI; EDC1; HCP; HI-30; HI30; IATIL; Intin4; ITI; ITIL; ITILC; UTI
UniProt ID: (Human) P02760, (Mouse) Q07456
Entrez Gene ID: (Human) 259, (Mouse) 11699
negative regulation of peptidase activity
negative regulation of endopeptidase activity
protein-chromophore linkage
protein catabolic process
protein maturation
receptor-mediated endocytosis
cell adhesion
female pregnancy
viral process
heme catabolic process
negative regulation of JNK cascade
negative regulation of immune response
