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Alomone Labs, LTD
alpha 1D-Adrenergic Receptor (extracellular) Polyclonal Antibody
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alpha 1D-Adrenergic Receptor (extracellular) Antibody (AAR-019-200UL) in ICC/IF
Expression of alpha 1D-Adrenoceptorin rat PC12 cells - Cell surface detection of alpha 1D-Adrenoceptor in intact living rat pheochromocytoma PC12 cells. A. Extracellular staining of cells using Anti- alpha 1D-Adrenergic Receptor (extracellular) Antibody (#AAR-019) (1:100)followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody . B. Merge of A and live view of the cells.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
AAR-019-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)EPVPPDERF*SGITEE, corresponding to amino acid residues 231-245 of rat alpha 1D-adrenoceptor with replacement of cysteine 240 (C240) with serine (*S), 3rd extracellular loop
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADA1D; adrenergic receptor delta1; adrenergic receptor, alpha 1d; adrenergic, alpha-1D-, receptor; alpha 1D-adrenoceptor; alpha 1D-adrenoreceptor; Alpha-1A adrenergic receptor; Alpha-1D adrenergic receptor; Alpha-1D adrenoceptor; Alpha-1D adrenoreceptor; Alpha-adrenergic receptor 1a; Alpha1delta-AR; RA42
基因别名: [a]1d; Adra-1; Adra1; ADRA1A; ADRA1D; Adrd1; alpha1D-AR; Gpcr8; Spr8
UniProt ID: (Rat) P23944
Entrez Gene ID: (Mouse) 11550, (Rat) 29413
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
aging
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
micturition
adrenergic receptor signaling pathway
adenylate cyclase-activating adrenergic receptor signaling pathway
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