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Invitrogen
alpha-2a Adrenergic Receptor Recombinant Rabbit Monoclonal Antibody (HL3725)
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alpha-2a Adrenergic Receptor Antibody (MA568296) in IHC (P)
Immunohistochemistry analysis of alpha-2a Adrenergic Receptor in paraffin-embedded mouse colon. Samples were incubated with alpha-2a Adrenergic Receptor recombinant monoclonal antibody (Product # MA568296) using a dilution of 1:100. Antigen Retrieval: Tris-EDTA buffer, pH 90, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA568296
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL3725
抗原
Recombinant protein encompassing a sequence within the Intracellular domain of human alpha 2a Adrenergic Receptor. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenergic receptor; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; alpha-2AAR; alpha2A-adrenergic receptor; OTTHUMP00000058849; subtype alpha2-C10
基因别名: Adra-2; Adra-2a; ADRA2A; ADRA2R; ADRAR; alpha(2A)AR; alpha2-C10; alpha2A; alpha2A-AR; AW122659
UniProt ID: (Mouse) Q01338
Entrez Gene ID: (Mouse) 11551
adrenergic receptor activity
alpha2-adrenergic receptor activity
protein kinase binding
alpha-2C adrenergic receptor binding
thioesterase binding
heterotrimeric G-protein binding
protein homodimerization activity
protein heterodimerization activity
epinephrine binding
norepinephrine binding
G-protein coupled receptor
positive regulation of cytokine production
acute inflammatory response
DNA replication
G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
cell-cell signaling
female pregnancy
negative regulation of norepinephrine secretion
positive regulation of cell migration
negative regulation of cAMP biosynthetic process
activation of protein kinase activity
activation of protein kinase B activity
cellular response to hormone stimulus
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
glucose homeostasis
fear response
positive regulation of MAP kinase activity
positive regulation of epidermal growth factor-activated receptor activity
positive regulation of vasodilation
negative regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
thermoception
negative regulation of lipid catabolic process
positive regulation of membrane protein ectodomain proteolysis
negative regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of uterine smooth muscle contraction
adrenergic receptor signaling pathway
adenylate cyclase-inhibiting adrenergic receptor signaling pathway
phospholipase C-activating adrenergic receptor signaling pathway
activation of MAPK activity by adrenergic receptor signaling pathway
positive regulation of wound healing
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