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Invitrogen
alpha E-Catenin/alpha N-Catenin Polyclonal Antibody
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产品信息
PA5-99602
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CTNNA1/CTNNA2, corresponding to a region within C-terminal amino acids.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CTNNA1/CTNNA2.
靶标信息
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha E-catenin; Alpha N-catenin; Alpha-catenin-related protein; alpha-E-catenin; alpha-N-catenin; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; Catenin alpha-1; Catenin alpha-2; Renal carcinoma antigen NY-REN-13
基因别名: CAP-R; CAP102; CAPR; CT114; CTNNA1; CTNNA2; CTNR; MDPT2
UniProt ID: (Human) P35221, (Human) P26232
Entrez Gene ID: (Human) 1495, (Human) 1496
ovarian follicle development
actin filament organization
cell adhesion
establishment or maintenance of cell polarity
negative regulation of neuroblast proliferation
aging
male gonad development
gap junction assembly
axon regeneration
adherens junction organization
cellular protein localization
odontogenesis of dentin-containing tooth
apical junction assembly
response to estrogen
positive regulation of smoothened signaling pathway
positive regulation of muscle cell differentiation
protein heterooligomerization
cellular response to indole-3-methanol
epithelial cell-cell adhesion
negative regulation of cell motility
negative regulation of integrin-mediated signaling pathway
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
cytoskeleton organization
axonogenesis
single organismal cell-cell adhesion
radial glia guided migration of Purkinje cell
dendrite morphogenesis
brain morphogenesis
regulation of synapse structural plasticity
prepulse inhibition
