Invitrogen

beta-2 Microglobulin/FCRN Polyclonal Antibody

查看其他2个beta-2 Microglobulin/FCRN抗体

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说明书
实验方案
问题与答案
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说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持

产品信息

PA5-80367

应用
建议稀释比
已发表文章

免疫组化（石蜡） (IHC (P))

1:500-1:2,000
-
产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human FCGRT & B2M Heterodimer Protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2787691

产品详细信息

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human FCGRT & B2M Heterodimer.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: beta chain of MHC class I molecules; beta-2-microglobin; Beta-2-microglobulin; Fc fragment of IgG, receptor, transporter, alpha; FcRn; FcRn alpha chain; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig; transmembrane alpha chain of the neonatal receptor

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基因别名: alpha-chain; B2M; CDABP0092; FCGRT; FCRN; HDCMA22P; IMD43

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UniProt ID: (Human) P61769, (Human) P55899

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Entrez Gene ID: (Human) 567, (Human) 2217

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功能
glycoprotein binding protein binding identical protein binding antigen binding IgG receptor activity IgG binding beta-2-microglobulin binding peptide antigen binding major histocompatibility complex protein
参与通路
retina homeostasis positive regulation of T cell mediated cytotoxicity antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent positive regulation of T cell cytokine production regulation of membrane depolarization negative regulation of neuron projection development antibacterial humoral response antigen processing and presentation of endogenous peptide antigen via MHC class I positive regulation of protein binding T cell differentiation in thymus protein refolding response to drug cellular protein metabolic process innate immune response response to cadmium ion positive regulation of receptor-mediated endocytosis regulation of defense response to virus by virus regulation of immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium iron ion homeostasis interferon-gamma-mediated signaling pathway cellular response to lipopolysaccharide cellular response to iron ion negative regulation of receptor binding positive regulation of receptor binding positive regulation of ferrous iron import into cell positive regulation of ferrous iron binding positive regulation of transferrin receptor binding IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor immune response antigen processing and presentation Fc-gamma receptor signaling pathway
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性能保障

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