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Invitrogen
beta-2 Microglobulin/FCRN Recombinant Rabbit Monoclonal Antibody (101)
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产品信息
MA5-30099
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
101
抗原
Recombinant Human FCGRT & B2M Protein (1-297, 1-119).
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Rat FCGRT & B2M.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B2M; beta 2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; Beta-2-microglobulin; Fc fragment of IgG receptor and transporter; Fc fragment of IgG, receptor, transporter, alpha; FcRn; FcRn alpha chain; HDCMA22P; heavy chain of the major histocompatibility complex class I-like Fc receptor; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig; neonatal fragment crystallizable Fc receptor FcRn; similar to Homo sapiens mRNA for beta 2-microglobulin with GenBank Accession Number AB021288; transmembrane alpha chain of the neonatal receptor; unnamed protein product
基因别名: alpha-chain; AMYLD6; B2M; CDABP0092; FcgammaRn; FCGRT; FCRN; HDCMA22P; IMD43; MHC1D4
UniProt ID: (Human) P61769, (Human) P55899
Entrez Gene ID: (Human) 567, (Human) 2217
IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
immune response
T cell mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity
response to molecule of bacterial origin
immune system process
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
peptide antigen assembly with MHC class I protein complex
peptide antigen assembly with MHC class II protein complex
positive regulation of T cell cytokine production
regulation of membrane depolarization
iron ion transport
cellular iron ion homeostasis
sensory perception of smell
learning or memory
response to metal ion
negative regulation of neuron projection development
antibacterial humoral response
antigen processing and presentation of endogenous peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class II
T cell differentiation in thymus
transferrin transport
regulation of iron ion transport
negative regulation of iron ion transport
protein refolding
innate immune response
regulation of erythrocyte differentiation
positive regulation of receptor-mediated endocytosis
negative regulation of receptor-mediated endocytosis
negative regulation of epithelial cell proliferation
negative regulation of neurogenesis
positive regulation of immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive regulation of T cell activation
protein homotetramerization
multicellular organismal iron ion homeostasis
antimicrobial humoral immune response mediated by antimicrobial peptide
cellular response to lipopolysaccharide
cellular response to iron ion
cellular response to iron(III) ion
cellular response to nicotine
amyloid fibril formation
positive regulation of cellular senescence
negative regulation of forebrain neuron differentiation
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