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Invitrogen
betacellulin Polyclonal Antibody
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betacellulin Antibody (PA5-95535) in IHC (P)
Immunohistochemistry analysis of betacellulin in paraffin-embedded human pancreatic cancer tissue. Antigen retrieval was performed on the tissue using citrate buffer (pH 6, 20 min) and blocked with 10% goat serum. Samples were incubated with betacellulin polyclonal antibody (Product # PA5-95535) at a 1 µg/mL dilution, followed by biotinylated goat anti-rabbit IgG (30 min, 37°C), and developed with Strepavid... View More
产品信息
PA5-95535
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human BTC recombinant protein (Position: D32-Y111).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - IHC: human mammary cancer tissue, human pancreatic cancer tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin
基因别名: BTC
UniProt ID: (Human) P35070
Entrez Gene ID: (Human) 685
MAPK cascade
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
positive regulation of urine volume
ERBB2 signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of mitotic nuclear division
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of fibroblast proliferation
positive regulation of cell division
regulation of cell motility
