Search
Agrisera
cAPX/Ascorbate peroxidase (cytosolic) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
产品信息
AS23-4940
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated peptide derived from APX1 and APX2 sequence of Arabidopsis thaliana.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
cAPX encodes a cytosolic class I heme-dependent ascorbate peroxidase that localizes predominantly to the cytosol, where it functions as a major enzymatic sink for hydrogen peroxide generated during normal metabolism and during oxidative, light, and abiotic/biotic stress responses. The canonical cAPX protein is a soluble ~250 amino acid monomeric polypeptide of the plant ascorbate peroxidase family that binds one noncovalently associated heme cofactor per subunit and adopts a predominantly alpha-helical peroxidase fold closely related to cytochrome c peroxidase; structural studies show assembly as a noncovalent homodimer in solution/crystals, with a conserved proximal histidine heme ligand and other conserved residues required for peroxide turnover and radical chemistry. Functionally, cAPX catalyzes the reduction of H2O2 to water using L-ascorbate as the preferred electron donor, thereby limiting ROS-mediated macromolecular damage while shaping H2O2-dependent signaling outputs; consistent with this role, genetic and physiological studies support cAPX as a central component of cellular redox homeostasis and stress acclimation, with loss or suppression of cAPX lowering detoxification capacity and promoting H2O2 accumulation during stress-associated processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ASCORBATE PEROXIDASE; ascorbate peroxidase 1; ATAPX01; ATAPX1; CS1; F24B9.2; F24B9_2; maternal effect embryo arrest 6; MEE6
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
