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Invitrogen
cIAP1 Recombinant Rabbit Monoclonal Antibody (HL1045)
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cIAP1 Antibody (MA5-42354) in WB
Western blot analysis of cIAP1 in Non-transfected (-) and transfected (+) 293T whole cell extracts (30 µg). Sample was separated with 7.5% SDS-PAGE, incubated with monoclonal cIAP1 antibody (Product # MA5-42354) at a dilution of 1:5000, and followed by HRP-conjugated anti-rabbit IgG.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-42354
产品规格
种属反应
Dog,
Cat,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL1045
抗原
Recombinant protein encompassing a sequence within the center region of human cIAP1. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
靶标信息
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis inhibitor 2; baculoviral IAP repeat-containing 3; Baculoviral IAP repeat-containing protein 2; C-IAP1; Cellular inhibitor of apoptosis 1; hIAP-2; IAP homolog B; IAP-2; inhibitor of apoptosis protein; Inhibitor of apoptosis protein 2; mIAP-2; mIAP2; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2
基因别名: API1; Api2; AW146227; BIRC2; Birc3; cIAP1; cIAP2; HIAP1; HIAP2; IAP1; IAP2; mcIAP1; MIAP1; MIAP2; MIHB; MIHC; rIAP1; RNF48
UniProt ID: (Mouse) Q62210
Entrez Gene ID: (Dog) 479464, (Mouse) 11797, (Rat) 60371
transcription coactivator activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein N-terminus binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
molecular_function
protease inhibitor
protein polyubiquitination
response to hypoxia
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
protein ubiquitination
regulation of toll-like receptor signaling pathway
regulation of apoptotic process
negative regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
protein heterooligomerization
regulation of cell cycle
regulation of necroptotic process
negative regulation of necroptotic process
necroptotic process
negative regulation of ripoptosome assembly involved in necroptotic process
positive regulation of protein K63-linked ubiquitination
positive regulation of protein K48-linked ubiquitination
positive regulation of protein monoubiquitination
regulation of nucleic acid-templated transcription
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
regulation of reactive oxygen species metabolic process
response to organonitrogen compound
response to organic cyclic compound
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to ethanol
response to cAMP
mitotic spindle assembly
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