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Invitrogen
delta Catenin Polyclonal Antibody
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图: 1 / 5
delta Catenin Antibody (PA5-17501) in ICC/IF
Immunofluorescence analysis of delta Catenin was performed using 70% confluent log phase MDA-MB-231 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with delta Catenin Rabbit Polyclonal Antibody (Product # PA5-17501) at 1:100 dilution in 0.1% BSA, incubated... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-17501
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the sequence of human catenin d-1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Armadillo protein; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin src; hp120ctn-1A; hp120ctn-1AB; hp120ctn-1ABC; hp120ctn-1AC; hp120ctn-1B; hp120ctn-2A; hp120ctn-2AB; hp120ctn-2ABC; hp120ctn-2AC; hp120ctn-2B; hp120ctn-3A; hp120ctn-3AB; hp120ctn-3ABC; hp120ctn-3AC; hp120ctn-3B; hp120ctn-4A; hp120ctn-4AB; hp120ctn-4ABC; hp120ctn-4AC; hp120ctn-4B; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); unnamed protein product
基因别名: BCDS2; CAS; Catns; CTNND; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN
UniProt ID: (Human) O60716, (Mouse) P30999
Entrez Gene ID: (Human) 1500, (Rat) 311163, (Mouse) 12388
receptor binding
protein binding
phosphatase inhibitor activity
phosphatase binding
cadherin binding
protein binding involved in cell-cell adhesion
protein sequestering activity
beta-catenin binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
cell adhesion molecule binding
protein tyrosine kinase binding
negative regulation of transcription from RNA polymerase II promoter
cell migration involved in sprouting angiogenesis
negative regulation of glucose transport
cell-cell adhesion mediated by cadherin
protein stabilization
cell-cell adhesion
regulation of postsynaptic membrane neurotransmitter receptor levels
positive regulation of protein localization to cell-cell junction
negative regulation of intracellular signal transduction
negative regulation of blood vessel branching
morphogenesis of a polarized epithelium
kidney development
cell adhesion
salivary gland morphogenesis
positive regulation of protein processing
epithelial cell differentiation involved in salivary gland development
glomerulus morphogenesis
positive regulation of peptidyl-tyrosine autophosphorylation
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