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Invitrogen
delta Catenin Recombinant Rabbit Monoclonal Antibody (RM353)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-33033
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RM353
抗原
A peptide corresponding to the C-terminus of human p120 catenin (Catenin delta-1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Specificity: reacts human p120 catenin (Catenin delta-1).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin-associated protein), delta 1; Catenin delta-1; hp120ctn-1A; hp120ctn-1AB; hp120ctn-1ABC; hp120ctn-1AC; hp120ctn-1B; hp120ctn-2A; hp120ctn-2AB; hp120ctn-2ABC; hp120ctn-2AC; hp120ctn-2B; hp120ctn-3A; hp120ctn-3AB; hp120ctn-3ABC; hp120ctn-3AC; hp120ctn-3B; hp120ctn-4A; hp120ctn-4AB; hp120ctn-4ABC; hp120ctn-4AC; hp120ctn-4B; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); unnamed protein product
基因别名: BCDS2; CAS; CTNND; CTNND1; KIAA0384; p120; p120(CAS); p120(CTN); P120CAS; P120CTN
Entrez Gene ID: (Human) 1500
negative regulation of transcription from RNA polymerase II promoter
cell migration involved in sprouting angiogenesis
negative regulation of glucose transport
cell-cell adhesion mediated by cadherin
protein stabilization
cell-cell adhesion
regulation of postsynaptic membrane neurotransmitter receptor levels
positive regulation of protein localization to cell-cell junction
negative regulation of intracellular signal transduction
negative regulation of blood vessel branching
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