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Bethyl Laboratories
eIF2B delta/EIF2B4 Polyclonal Antibody
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eIF2B delta/EIF2B4 Antibody (A302-982A) in IHC (P)
Detection of human eIF2B delta/EIF2B4 by immunohistochemistry. Samples: FFPE sections of human colon carcinoma and breast carcinoma. Antibody: Affinity purified rabbit anti-eIF2B delta/EIF2B4 (Product # A302-982A) (Lot 1) used at a dilution of 1:200 (1 µg/mL). Detection: DAB.
产品信息
A302-982A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 50 and 100 of human Eukaryotic Translation Initiation Factor 2B, Subunit 4 delta, 67kDa.
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp586J0119; eIF-2B GDP-GTP exchange factor subunit delta; eIF2B GDP-GTP exchange factor subunit delta; eukaryotic translation initiation factor 2B subunit 4 delta; eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; translation initiation factor eIF-2b delta subunit; Translation initiation factor eIF2B subunit delta
基因别名: EIF-2B; EIF2B; EIF2B4; EIF2BD; EIF2Bdelta
UniProt ID: (Human) Q9UI10
Entrez Gene ID: (Human) 8890
ovarian follicle development
translational initiation
regulation of translation
response to heat
response to glucose
oligodendrocyte development
L-methionine biosynthetic process from methylthioadenosine
negative regulation of translational initiation in response to stress
myelination
response to peptide hormone
positive regulation of GTPase activity
negative regulation of translational initiation
cellular response to stimulus
