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PA5-41837 detects HNRPH3 in WB and IHC applications.
Peptide sequence: DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Heterogeneous nuclear ribonucleoprotein 2H9; Heterogeneous nuclear ribonucleoprotein H3; heterogeneous nuclear ribonucleoprotein H3 (2H9); hnRNP 2H9; hnRNP H3
基因别名: 2H9; HNRNPH3; HNRPH3
UniProt ID: (Human) P31942
Entrez Gene ID: (Human) 3189