Product References
The Expression of Cellular Prion Protein, PrPC, Favors pTau Propagation and Blocks NMDAR Signaling in Primary Cortical Neurons.
Cells
Rivas-Santisteban R,Raïch I,Aguinaga D,Saura CA,Franco R,Navarro G
MA5-17139 was used in Immunocytochemistry-immunofluorescence to identify NMDA-PrPC complexes where PrPC was capable of blocking NMDAR-mediated effects.
Wed Jan 11 00:00:00 EST 2023
FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape.
Theranostics
Wu L,Xu Y,Zhao H,Zhou Y,Chen Y,Yang S,Lei J,Zhang J,Wang J,Wu Y,Li Y
MA5-17139 was used in Flow Cytometry to uncover an unrecognized regulatory role of the FcγRIIB in abnormal differentiation of MDSCs during cancer development and suggest a potential therapeutic target for anti-tumor therapy.
Thu Mar 10 00:00:00 EST 2022
FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape.
Theranostics
Wu L,Xu Y,Zhao H,Zhou Y,Chen Y,Yang S,Lei J,Zhang J,Wang J,Wu Y,Li Y
MA5-17139 was used in Flow Cytometry to uncover an unrecognized regulatory role of the FcγRIIB in abnormal differentiation of MDSCs during cancer development and suggest a potential therapeutic target for anti-tumor therapy.
Thu Mar 10 00:00:00 EST 2022
Riboflavin attenuates tartrazine toxicity in the cerebellar cortex of adult albino rat.
Scientific reports
Ismail OI,Rashed NA
MA5-17139 was used in Immunohistochemistry to investigate the impact of tartrazine administration on the cerebellum and to assess the potential role of riboflavin co-administration in the adult male albino rat.
Fri Nov 11 00:00:00 EST 2022
Local Delivery of Pirfenidone by PLA Implants Modifies Foreign Body Reaction and Prevents Fibrosis.
Biomedicines
Fayzullin A,Churbanov S,Ignatieva N,Zakharkina O,Tokarev M,Mudryak D,Khristidis Y,Balyasin M,Kurkov A,Golubeva EN,Aksenova NA,Dyuzheva T,Timashev P,Guller A,Shekhter A
MA5-17139 was used in Immunohistochemistry (Paraffin) to understand the possible role of Pirfenidone and polyactic acid in reducing peri-implant fibrosis in post-surgery.
Wed Jul 21 00:00:00 EDT 2021
Local Delivery of Pirfenidone by PLA Implants Modifies Foreign Body Reaction and Prevents Fibrosis.
Biomedicines
Fayzullin A,Churbanov S,Ignatieva N,Zakharkina O,Tokarev M,Mudryak D,Khristidis Y,Balyasin M,Kurkov A,Golubeva EN,Aksenova NA,Dyuzheva T,Timashev P,Guller A,Shekhter A
MA5-17139 was used in Immunohistochemistry (Paraffin) to understand the possible role of Pirfenidone and polyactic acid in reducing peri-implant fibrosis in post-surgery.
Wed Jul 21 00:00:00 EDT 2021
Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tan H,Song Y,Chen J,Zhang N,Wang Q,Li Q,Gao J,Yang H,Dong Z,Weng X,Wang Z,Sun D,Yakufu W,Pang Z,Huang Z,Ge J
MA5-17139 was used in Immunocytochemistry to construct a platelet-like fusogenic liposome (PLPs) to deliver contents to the cytoplasm of target cells.
Sun Aug 01 00:00:00 EDT 2021
RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis.
Cancer immunology research
Wu L,Zhang X,Zheng L,Zhao H,Yan G,Zhang Q,Zhou Y,Lei J,Zhang J,Wang J,Xin R,Jiang L,Peng J,Chen Q,Lam SM,Shui G,Miao H,Li Y
MA5-17139 was used in Flow cytometry/Cell sorting to provide molecular basis for the regulation of RIPK3-mediated, lipid metabolic reprogramming of TAMs, thus highlighting a potential strategy for targeting the immunometabolism of HCC.
Fri May 01 00:00:00 EDT 2020
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sadler R,Cramer JV,Heindl S,Kostidis S,Betz D,Zuurbier KR,Northoff BH,Heijink M,Goldberg MP,Plautz EJ,Roth S,Malik R,Dichgans M,Holdt LM,Benakis C,Giera M,Stowe AM,Liesz A
MA5-17139 was used in Immunohistochemistry to test the hypothesis that short-chain fatty acids (SCFAs), key bioactive microbial metabolites, are the missing link along the gut-brain axis and might be able to modulate recovery after experimental stroke.
Wed Jan 29 00:00:00 EST 2020
TRPV4 Plays a Role in Matrix Stiffness-Induced Macrophage Polarization.
Frontiers in immunology
Dutta B,Goswami R,Rahaman SO
MA5-17139 was used in Immunohistochemistry to determine key aspects of the molecular mechanism by which mechanical cues regulate macrophage polarization.
Mon May 31 00:00:00 EDT 2021
TRPV4 Plays a Role in Matrix Stiffness-Induced Macrophage Polarization.
Frontiers in immunology
Dutta B,Goswami R,Rahaman SO
MA5-17139 was used in Immunohistochemistry to determine key aspects of the molecular mechanism by which mechanical cues regulate macrophage polarization.
Mon May 31 00:00:00 EDT 2021
S100A9 Regulates MDSCs-Mediated Immune Suppression via the RAGE and TLR4 Signaling Pathways in Colorectal Carcinoma.
Frontiers in immunology
Huang M,Wu R,Chen L,Peng Q,Li S,Zhang Y,Zhou L,Duan L
MA5-17139 was used in Flow Cytometry to investigate the effect and molecular mechanisms of S100A9 on the accumulation and immunosuppressive function of myeloid-derived suppressor cells in colorectal carcinoma.
Tue Nov 10 00:00:00 EST 2020
A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell-Potentiated Colorectal Carcinogenesis.
Cancer research
Yan G,Zhao H,Zhang Q,Zhou Y,Wu L,Lei J,Wang X,Zhang J,Zhang X,Zheng L,Du G,Xiao W,Tang B,Miao H,Li Y
MA5-17139 was used in Flow cytometry/Cell sorting to demonstrate a novel signaling circuit by which RIPK3 and PGE2 regulate tumor immunity.
Mon Oct 01 00:00:00 EDT 2018