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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; Progestin and adipoQ receptor family member V
基因别名: MPRG; PAQR5
Entrez Gene ID: (Human) 54852