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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody reacts to human serine/threonine-protein kinase mTOR. This antibody may also react to mouse or rat mTOR, as predicted by immunogen homology.
Predicted Reactivity: Mouse, Rat
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; m-TOR; Mammalian target of rapamycin; Mechanistic target of rapamycin; mTOR; mTORC1; Rapamycin and FKBP12 target 1; Rapamycin target protein 1; Serine/threonine-protein kinase mTOR; Tyrosine-protein kinase mTOR
基因别名: FRAP; FRAP1; FRAP2; MTOR; RAFT1; RAPT1
Entrez Gene ID: (Human) 2475