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Invitrogen
p40 Polyclonal Antibody
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p40 Antibody (PA5-115708) in ICC/IF
Immunocytochemistry analysis of p40 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115708) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
产品信息
PA5-115708
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RABEPK(Accession Q7Z6M1), corresponding to amino acid residues Q166-F216.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total p40.
靶标信息
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 40 kDa Rab9 effector protein; p40; Rab9 effector p40; Rab9 effector protein with kelch motifs
基因别名: 8430412M01Rik; 9530020D24Rik; AV073337; bA65N13.1; C87311; p40; RAB9P40; RABEPK; RGD1310612
UniProt ID: (Human) Q7Z6M1, (Rat) Q4V8F4, (Mouse) Q8VCH5
Entrez Gene ID: (Human) 10244, (Rat) 296649, (Mouse) 227746
