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Invitrogen
p53 (R175H Mutant) Recombinant Rabbit Monoclonal Antibody (HL1129)
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图: 1 / 3
p53 (R175H Mutant) Antibody (MA5-46935) in ICC/IF
Immunofluorescent analysis of p53 (R175H Mutant) in mock and transfected 293T cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: p53 (R175H Mutant) stained by p53 (R175H Mutant) monoclonal antibody (Product # MA5-46935) diluted at 1:1900. Blue: Fluoroshield with DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-46935
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL1129
抗原
Carrier-protein conjugated synthetic peptide surrounding mutant R175H of human p53. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
靶标信息
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains|The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism|Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome|Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms|Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277)
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosyltransferase diphtheria toxin-like 1; ADPRT 1; ARTD1; BCC7; BMFS5; Carboxypeptidase A1; Casein kinase I isoform alpha; Casein kinase I isoform alpha-like; CASP-1; Caspase-1; CK1; CKI-alpha; CKI-alpha-like; DNA ADP-ribosyltransferase PARP1; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; ICE; IL-1BC; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; LFS1; Microtubule-associated protein tau; NAD(+) ADP-ribosyltransferase 1; Neurofibrillary tangle protein; p45; P53; Paired helical filament-tau; PARP-1; PHF-tau; Poly [ADP-ribose] polymerase 1; Poly[ADP-ribose] synthase 1; Protein poly-ADP-ribosyltransferase PARP1; TRP53; Tubulin beta-2 chain; Tubulin beta-2C chain; Tubulin beta-4B chain; tumor protein p53
基因别名: ADPRT; CASP1; CPA; CPA1; CSNK1A1; CSNK1A1L; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1H3A; HIST1H3B; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; IL1BC; IL1BCE; MAPT; MAPTL; MTBT1; PARP1; PPOL; TAU; TUBB2C; TUBB4B
Entrez Gene ID: (Human) 834, (Human) 1357, (Human) 1452, (Human) 122011, (Human) 8350, (Human) 4137, (Human) 142, (Human) 10383
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