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Proteintech
14-3-3 Polyclonal Antibody, CoraLite® Plus 647
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产品信息
CL647-14503
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein
偶联物
激发/发射光谱
654/674 nm
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR VISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK MKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE ILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN
靶标信息
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 14-3-3 protein T-cell; 14-3-3 protein tau; 14-3-3 protein theta; 14-3-3 tau; 14-3-3 theta; OTTHUMP00000165887; Protein HS1; protein tau; protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
基因别名: 14-3-3; 14-3-3t; 1C5; 2700028P07Rik; AA409740; AU021156; HS1; R74690; YWHAQ
UniProt ID: (Human) P27348, (Rat) P68255, (Mouse) P68254
Entrez Gene ID: (Human) 10971, (Rat) 25577, (Mouse) 22630
protein targeting
small GTPase mediated signal transduction
substantia nigra development
negative regulation of ion transmembrane transport
negative regulation of transcription, DNA-templated
membrane organization
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
signal transduction
