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Invitrogen
14-3-3 eta Polyclonal Antibody
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14-3-3 eta Antibody (PA5-29774) in WB
Western Blot analysis of 14-3-3-eta was performed by separating 30 µg of various whole cell extracts by 12% SDS-PAGE. Proteins were transferred to a membrane and probed with a 14-3-3 eta Polyclonal Antibody (Product # PA5-29774) at a dilution of 1:1000 and a HRP-conjugated anti-rabbit IgG secondary antibody.
产品信息
PA5-29774
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human 14-3-3 eta. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (83%), Xenopus laevis (91%), Rabbit (98%), Chicken (97%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 14-3-3 eta; 14-3-3 protein eta; 1433F; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA114-3-3 eta
基因别名: YWHA1; YWHAH
UniProt ID: (Human) Q04917
Entrez Gene ID: (Human) 7533
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
substantia nigra development
glucocorticoid receptor signaling pathway
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
membrane organization
membrane depolarization during action potential
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of sodium ion transmembrane transporter activity
