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Invitrogen
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PA1-29193 detects PHAS-I from human samples.
PA1-29193 has been successfully used in Western blot applications.
The PA1-29193 immunogen is: Synthetic peptide corresponding to the C-terminus of human PHAS-I protein
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。