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Invitrogen
4EBP1 Recombinant Rabbit Monoclonal Antibody (ARC0374)
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4EBP1 Antibody (MA5-35226) in IHC (P)
Immunohistochemical analysis of 4EBP1 performed on paraffin embedded human lung cancer using a 4EBP1 monoclonal antibody (Product # MA5-35226) at a dilution of 1:100. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000.
产品信息
MA5-35226
产品规格
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC0374
抗原
A synthetic peptide corresponding to amino acids 1-100 of human 4EBP1.
偶联物
形式
Liquid
浓度
0.25 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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