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Proteintech
AARE Polyclonal Antibody
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产品信息
14758-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AARE Fusion Protein Ag6511 (381-732 aa encoded by BC000362)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can recognize at least 2 isoforms of APH.
Immunogen sequence: AQRSRQDLF AVDTQVGTVT SLTAGGSGGS WKLLTIDQDL MVAQFSTPSL PPTLKVGFLP SAGKEQSVLW VSLEEAEPIP DIHWGIRVLQ PPPEQENVQY AGLDFEAILL QPGSPPDKTQ VPMVVMPHGG PHSSFVTAWM LFPAMLCKMG FAVLLVNYRG STGFGQDSIL SLPGNVGHQD VKDVQFAVEQ VLQEEHFDAS HVALMGGSHG GFISCHLIGQ YPETYRACVA RNPVINIASM LGSTDIPDWC VVEAGFPFSS DCLPDLSVWA EMLDKSPIRY IPQVKTPLLL MLGQEDRRVP FKQGMEYYRA LKTRNVPVRL LLYPKSTHAL SEVEVESDSF MNAVLWLRTH LGS (381-732 aa encoded by BC000362)
靶标信息
APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AARE; Acyl-peptide hydrolase; Acylamino-acid-releasing enzyme; Acylaminoacyl-peptidase; acylpeptide hydrolase; APH; MGC2178; N-acylaminoacyl peptide hydrolase; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase
基因别名: AARE; ACPH; APEH; APH; D3F15S2; D3S48E; DNF15S2; OPH
UniProt ID: (Human) P13798, (Mouse) Q8R146, (Rat) P13676
Entrez Gene ID: (Human) 327, (Mouse) 235606, (Rat) 24206
