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Proteintech
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Immunogen sequence: THLLNWALR QTLGPGTEQQ GSHLNPEQLR LDVTTQTPLT PEQLRAVENT VQEAVGQDEA VYMEEVPLAL TAQVPGLRSL DEVYPDPVRV VSVGVPVAHA LDPASQAALQ TSVELCCGTH LLRTGAVGDL VIIGDRQLSK GTTRLLAVTG EQAQQARELG QSLAQEVKAA TERLSLGSRD VAEALRLSKD IGRLIEAVET AVMPQWQRRE LLATVKMLQR RANTAIRKLQ MGQAAKKTQE LLERHSKGPL IVDTVSAESL SVLVKVVRQL CEQAPSTSVL LLSPQPMGKV LCACQVAQGA MPTFTAEAWA LAVCSHMGGK AWGSRVVAQG TGSTTDLEAA LSIAQTYALS QL (635-985 aa encoded by BC131728)
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AARS2; alanine tRNA ligase 2, mitochondrial (putative); Alanine--tRNA ligase, mitochondrial; Alanyl-tRNA synthetase; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; AlaRS; bA444E17.1; probable alanyl-tRNA synthetase, mitochondrial
基因别名: AARS2; AARSL; COXPD8; KIAA1270; LKENP; MT-ALARS; MTALARS
UniProt ID: (Human) Q5JTZ9
Entrez Gene ID: (Human) 57505