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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QLSNGTTRLLA VTGEQAQQAR ELGQSLAQEV KAATERLSLG SRDVAEALRL SKDIGRLIEA VETAVMP
Highest antigen sequence identity to the following orthologs - mouse 75%, rat 75%.
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alanine--tRNA ligase, mitochondrial; Alanyl-tRNA synthetase; AlaRS; bA444E17.1; Protein lactyltransferase AARS2
基因别名: AARS2; AARSL; KIAA1270
Entrez Gene ID: (Human) 57505