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Invitrogen
ABCA1 Monoclonal Antibody (3A1-891.3), FITC
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产品信息
MA5-28156
产品规格
宿主/亚型
Rat
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3A1-891.3
抗原
Synthetic peptide corresponding to aa 215-233
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
运输条件
Wet ice
RRID
产品详细信息
Rat anti Mouse ABCA1 antibody, clone 3A1-891.3 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1).
靶标信息
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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