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Abnova
ABO Monoclonal Antibody (1B7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00000028-M08
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1B7
抗原
ABO (NP_065202.2, 273 a.a. approximately 354 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: SVQEVQRLTR ACHQAMMVDQ ANGIEAVWHD ESHLNKYLLR HKPTKVLSPE YLWDQQLLGW PAVLRKLRFT AVPKNHQAVR NP
靶标信息
Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); alpha 1-3-N-acetylgalactosaminyltransferase; Any polymorphism or mutation that changes the activity or specificity of the encoded enzyme may therefore alter the ABO phenotype.; B (A) alpha 1; B(A) alpha-1,3-galactosyltransferase; Bel; BGAT; glycoprotein-fucosylgalactoside alpha-galactosyltransferase; histo-blood group A transferase (UDP-GalNAc); histo-blood group A2 transferase; histo-blood group ABO system transferase; red blood cell ABO blood group B antigen 648C>G results in amino acid change of transferase; transfer products of ABO group A antigen 297A>G, 467C>T, 1003G>A lead to amino acid changes; transferase A; A glycosyltransferase; transferase B; Unknown; unnamed protein product
基因别名: A3GALNT; A3GALT1; GTA; GTB; NAGAT
UniProt ID: (Human) P16442
Entrez Gene ID: (Human) 28
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