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Proteintech
ACADL Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
17526-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.27 mg/mL
规格
40.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
The size difference between the precursor and mature rat LCAD has been estimated to be 3 kDa on the basis of SDS-PAGE. Defects in ACADL are a cause of acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD). This antibody is specific to ACADL.
靶标信息
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD long chain acyl-CoA dehydrogenase; long chain acyl-CoA dehydrogenase precursor (EC 1.3.99.2); long-chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase, mitochondrial; unnamed protein product
基因别名: ACAD4; ACOADA; LCAD
UniProt ID: (Human) P28330, (Rat) P15650, (Mouse) P51174
Entrez Gene ID: (Human) 33, (Rat) 25287, (Mouse) 11363
acyl-CoA dehydrogenase activity
long-chain-acyl-CoA dehydrogenase activity
protein binding
oxidoreductase activity, acting on the CH-CH group of donors
very-long-chain-acyl-CoA dehydrogenase activity
protein homodimerization activity
flavin adenine dinucleotide binding
medium-chain-acyl-CoA dehydrogenase activity
temperature homeostasis
fatty acid catabolic process
response to cold
lipid catabolic process
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
regulation of cholesterol metabolic process
positive regulation of cold-induced thermogenesis
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
