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Proteintech
ACAT2 Polyclonal Antibody
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产品信息
14755-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ACAT2 Fusion Protein Ag6503 (1-397 aa encoded by BC000408)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MNAGSDPVV IVSAARTIIG SFNGALAAVP VQDLGSTVIK EVLKRATVAP EDVSEVIFGH VLAAGCGQNP VRQASVGAGI PYSVPAWSCQ MICGSGLKAV CLAVQSIGIG DSSIVVAGGM ENMSKAPHLA YLRTGVKIGE MPLTDSILCD GLTDAFHNCH MGITAENVAK KWQVSREDQD KVAVLSQNRT ENAQKAGHFD KEIVPVLVST RRGLIEVKTD EFPRHGSNIE AMSKLKPYFL TDGTGTVTPA NASGINDGAA AVVLMKKSEA DKRGLTPLAR IVSWSQVGVE PSIMGIGPIP AIKQAVTKAG WSLEDVDIFE INEAFAAVSA AIVKELGLNP EKVNIEGGAI ALGHPLGASG CRILVTLLHT LERMGRSRGV AALCIGGGMG IAMCVQRE (1-397 aa encoded by BC000408)
靶标信息
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acetoacetyl Coenzyme A thiolase; Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2; acetyl-Coenzyme A acetyltransferase 3; AE1; BND3; CD233; Cytosolic acetoacetyl-CoA thiolase; DI; EMPB3; EPB3; FR; RTA1A; SW; t-complex protein 1, related sequence 1; WD; WD1; WR
基因别名: Ab2-076; ACAT2; Acat3; ACTL; AW742799; Tcp-1x; Tcp1-rs1
UniProt ID: (Human) Q9BWD1, (Rat) Q5XI22, (Mouse) Q8CAY6
Entrez Gene ID: (Human) 39, (Rat) 308100, (Mouse) 110460
